Y-TZP is also considered to be incredibly advantageous from an immunological point of view, as this ceramic implant material causes an extremely low inflammatory stimulus of the peri-implant tissue and consequently attracts adjacent soft tissue to a particularly high degree. For this reason, among others, healthy soft-tissue conditions with an unprecedented degree of soft-tissue adaptation can be observed in placed Patent™ Implants even after more than a decade of wear. This so-called "soft-tissue seal" is particularly advantageous because it is able to prevent pathogenic bacteria in the oral cavity from penetrating past the implant into the deeper tissue, where they would promote, among other things, peri-implant inflammation (in the worst case, periimplantitis) and marginal bone loss. Long-term scientific studies have demonstrated just that: Karapataki et al. for example, in a retrospective study, documented over 90 placed Patent™ Implants up to 12 years of function and found no signs of periimplantitis in any of them. Furthermore, Becker et al. found stable marginal bone levels and healthy soft-tissue conditions (with gingival recession of <1 mm) in placed Patent™ Implants after 9 years of wear as a result of their prospective long-term study at Heinrich-Heine University Düsseldorf.
Due to the low thermal conductivity of Y-TZP, users of the Patent™ Dental Implant System are encouraged to use moderate torques when screwing in the implant in view of the high roughness endosseous implant surface, which is a prerequisite for the scientifically proven superior osseointegration of the Patent™ Implant, as heat developing on the implant surface as a result of excessive torque may compromise the vitality of the periimplant bone during healing.